Understanding the origin of life requires addressing a collection of overlapping scientific questions. We've made a lot of progress toward explaining how simple chemicals present on an early Earth built the complex molecules used by life and how some of those chemicals built the first genetic/catalytic molecules. But we're much further from understanding a key conundrum: How did membranes end up surrounding the first cells?

It's relatively easy to make membranes spontaneously form in water, and they'll enclose anything dissolved in that water, including nucleic acids. But the membranes then cut their interior off from everything else in the solution. Any interesting chemical reactions enclosed there would eat through the raw materials and grind to a halt.

Now, a lab at the University of Minnesota has announced that it has developed a simplified system in which a membrane encloses some genetic material but can continually import new materials supplied to it. The system also spontaneously divides, producing a few generations of "offspring" before things start failing. It's still extremely dependent upon human intervention, but it might provide a new avenue to explore questions about the origin of life and what a truly minimalistic form of life might look like.

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Near the end of May, the Office of Management and Budget (OMB) proposed a new rule that would govern how the federal government handles the grants it issues, including those that fund the vast majority of scientific research in the US.

If formalized, the rule would make political priorities the prime determinant of what science gets funded and sideline the opinions of scientific experts. Grants could be canceled due to political whims, and new layers of bureaucracy would inhibit basic scientific activities like publishing papers and attending conferences. Unlike the executive orders it echoes, it would have the force of law behind it and be significantly harder to challenge in court.

Before coming into force, however, the proposal must go through a process that includes public feedback and (potentially) changes in response. The deadline for that feedback—Monday, July 13—is rapidly approaching.

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